Angioid streaks in Jamaican patients with homozygous sickle cell disease.
نویسندگان
چکیده
Angioid streaks were observed in 21 of 242 patients with homozygous sickle cell disease. Two morphological types were observed. There is no evidence that angioid streaks in Jamaican patients are related to pseudoxanthoma elasticum.
منابع مشابه
Ocular findings of elderly cases of homozygous sickle-cell disease in Jamaica.
The ocular fingings in 60 patients with homozygous sickle-cell disease over the age of 40 years have been described. Peripheral retinal vessel disease was common and appeared to increase with age. Retinitis proliferans was common among older patients in the group. Angioid streaks occurred in 13 (22 per cent) patients.
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Angioid streaks are visible irregular crack-like dehiscences in Bruch's membrane that are associated with atrophic degeneration of the overlying retinal pigmented epithelium. Angioid streaks may be associated with pseudoxanthoma elasticum, Paget's disease, sickle-cell anemia, acromegaly, Ehlers-Danlos syndrome, and diabetes mellitus, but also appear in patients without any systemic disease. Pat...
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The most characteristic ocular lesions in pseudoxanthoma elasticum are the angioid streaks which may be seen in about 85 per cent. of cases. The associated features in the fundus are a peculiar mottled appearance (Shimizu, I96I), peau d'orange (Smith, Gass, and Justice, I964), and yellowish-white spots (salmon spots). While most subjects showing angioid streaks have pseudoxanthoma elasticum, cl...
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ورودعنوان ژورنال:
- The British journal of ophthalmology
دوره 65 5 شماره
صفحات -
تاریخ انتشار 1981